User blog comment:Kuro-kon/Question about starting a space marine Chapter/@comment-24909831-20140819084120

I don't think there would be a problem that certain chapter gets deployed with the same guard regiment(s) durign campaign or crusade, but to have long friendship between chapter and guard regiment seems unlikely for various reasons. If I put it bluntly, Marines are no humans in sense of friendship and attachment. They of course recognise valorous guard regiments, but the real friendship and trust between chapter and regiment seems (to me, at least) unlikely.

I have a chapter that frequently gets deployed with guard regiments, though the regiments vary every time. See White Tigers if you want some inspiration, I think it is pretty canon friendly.

Also, as I'm aware of, Xenos taint is purged with fire, no exceptions. There was Catachan regiment who was killed by inquisition to the last man, because they got influenced by Tyranids. There is no way that zealous Marines would tolerate such heresy.